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What is folic acid deficiency? Folic acid deficiency is a deficiency of vitamin B9 (folic acid). Folic acid is a water-soluble vitamin that can only be taken into the body through food and supplements. The body uses folic acid to make and repair DNA (genetic material in cells) and produce red blood cells, which carry oxygen throughout the body.
Summary of folate and L-Methylfolate Folate, a B vitamin, is essential for building the body's genetic material. Many foods naturally contain folate, especially green leafy vegetables. Many manufacturers also use folic acid, a synthetic form of folate, to fortify cereals and grains. In addition, folic acid is provided as a supplement.
Supplemental source of folic acid and L-Methylfolate Although researchers once thought folic acid was more easily absorbed than folate, they now know that its metabolism is very slow. In addition, most of the folic acid you consume will remain metabolized and linger in the system. There are also concerns that the excessive accumulation of unmetabolized folic acid may promote tumor growth, although this has not been clearly confirmed.
5-MTHF and L-Methylfolate 5-MTHF is another form of folic acid supplement. In the United States, about 25% of Hispanics, 10%-15% of whites and 6% of African Americans have a genetic variation called MTHFR C677T. This variation further affects the ability to metabolize folic acid.
Something about folic acid Folic acid is the synthetic form of folate and is the most common form of supplementation. Manufacturers also use it for food fortification.
What are the side effects of folic acid? If you are pregnant, nursing, or lack folic acid, your provider may advise you to take folic acid. As an essential nutrient from food, folic acid is not associated with side effects or risks. However, taking supplements such as folic acid may have potential side effects. These side effects may be common or severe.
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