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Best Uses for L-5-methylfolate: Ensure your body’s supply of an active form of folic acid Support mood and overall mental wellness Reduce homocysteine levels and lower risk for heart disease Prevent neural tube defects in pregnancy L-5-methylfolate is important in any instance where folic acid (folate) is needed. Women should ensure they receive enough folate in their diets and supplement if they’re unsure.
So, What Does L-5-Methylfolate Do L-5-Methylfolate is the most important active form of folate. Many people aren’t able to produce this form of folic acid, due to liver dysfunction or intestinal issues. Another major reason is that the majority of Americans (3 out of 5) who have genetic variations in the enzyme known as L-5-Methylfolate-reductase cannot fully convert folic acid into the more useful 5-Methyltetrahydrofolate.
You need supplementary l-5-methylfolate The folate we obtain from the diet must be converted to its active form – called L-5-methylfolate – before it can help power the methylation cycle. However, approximately 60% of U.S. adults have a genetic mutation that makes it challenging for their bodies to create enough L-5-methylfolate from dietary sources.
Depression and L-5-methylfolate The role of L-5-methylfolate in the treatment of patients with depression has once again been highlighted by an article published in the American Journal of Psychiatry in 2016.
What does L-Methylfolate do for you L-Methylfolate is a medical food for use in people who have conditions related to folate deficiency. L-Methylfolate is also used in people with major depressive disorder who have folate deficiency, or in people with schizophrenia who have hyperhomocysteinemia related to folate deficiency.
Are L-5-Methyltetrahydrofolate and folic acid the same? Folate or folic acid is in fact Vitamin B9. L-5-Methyltetrahydrofolate is the more active and natural form of folate. Folic acid is the synthetic form of folate.
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