Folic acid is the synthetic form of folate that is commonly found in supplements and fortified foods. However, folic acid needs to be converted into its active form, 5-MTHF, in order to be utilized by the body.
Some people have a genetic variation that reduces their ability to convert folic acid into active folate, which can lead to a deficiency. Taking supplements of active folate may be beneficial for these individuals, as well as pregnant women and those with certain medical conditions that affect folate metabolism.

Magnafolate is the unique patent protected C crystalline Calcium L-5-methyltetrahydrofolate(L-5-MTHF Ca) which can get the purest and most stable bio-active folate.
Magnafolate can be absorbed directly, no metabolism, suitable for all kinds of people including MTHFR gene mutation. While food folate and folic acid need to undergo several biochemical conversions in the body to become L-5-MTHF.