Calcium L-5-methyltetrahydrofolate CAS

Calcium L-5-methyltetrahydrofolate (CAS No. 151533-22-1) is an important organic compound, also known as calcium methyltetrahydrofolate or L-5-MTHF-Ca. It is a water soluble crystalline powder with excellent biological activity and stability and has been widely used in food, pharmaceutical and nutraceutical applications.

The chemical structure of calcium L-5-methyltetrahydrofolate is similar to that of folic acid, a polyacid containing a five-membered ring with the molecular formula C20H23CaN7O6. Its main role is to promote methionine metabolism, to participate in DNA and RNA synthesis, repair and methylation reactions, and to play an important role in the nervous system and immune system.
Calcium L-5-methyltetrahydrofolate has been widely used in food and health products as a nutrient and bioactive substance. It strengthens the immune system, improves blood circulation, reduces fatigue and stress, and has a protective effect on organs such as the skin, cardiovascular, eyes and brain. In addition, calcium L-5-methyltetrahydrofolate is also widely used in medicine for the treatment and prevention of cardiovascular diseases, neurological disorders, anaemia and cancer.

The stability of calcium L-5-methyltetrahydrofolate is key to its widespread use. As it is susceptible to oxidation and degradation, appropriate preservation and processing methods need to be employed to ensure its biological activity and effectiveness. In addition, the intake of calcium L-5-methyltetrahydrofolate needs to be controlled within appropriate limits to avoid adverse effects on the human body.

In conclusion, calcium L-5-methyltetrahydrofolate is an important nutrient and biologically active substance that has been widely used in food, pharmaceutical and nutraceutical applications.


Magnafolate is the unique patent protected C crystalline L-5-Methyltetrahydrofolate Calcium salt (L-5-MTHF Ca) which can get the purest and most stable bio-active folate.


Magnafolate can be absorbed directly, no metabolism, suitable for all kinds of people including MTHFR gene mutation. 

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