Folate is a water-soluble vitamin that plays an important role in the body, including participating in DNA and RNA synthesis, maintaining the normal function of the nervous system, and promoting the production of red blood cells.

In addition, Folate can actually prevent the occurrence of depression, which can also be understood as follows: to a certain extent, a lack of Folate can lead to depression.

Folate is widely found in foods such as green vegetables, fresh fruits, and animal livers. Due to its unstable structure, it is easily lost, and the natural Folate in foods mainly exists in the form of polyglutamic acid. After human ingestion, it needs to go through a complex process to be absorbed.

Folate is easily lost due to its unstable structure, and the folate in food mainly exists in the form of polyglutamic acid. After human ingestion, it needs to go through a complex process to be absorbed.

During the absorption of folate, the lack of alcohol, drugs or other nutrients will cause an impact, so the bioavailability of folate is relatively low. If the daily intake of folate-rich foods is small and no additional folate supplements are taken, it is very likely to cause folate deficiency.

On the one hand, low levels of Folate can affect the synthesis of monoamine neurotransmitters such as serotonin, adrenaline, and dopamine, promoting depression;

on the other hand, it can also affect homocysteine metabolism, forming hyperhomocysteinemia, promoting or accelerating the occurrence and development of depression.

In addition, hyperhomocysteinemia exacerbates oxidative stress, mitochondrial dysfunction and apoptosis in human dopaminergic cells, resulting in disruption of optimal dopamine neurotransmitter biosynthesis.

Dopamine is the "carrier" of emotions such as happiness and excitement in the human body, and the disruption of its synthesis and reduction in its quantity contributes to a certain extent to the development of depression.

Although it is not a lack of Folate that will definitely lead to depression, early prevention is definitely correct. Increase Folate supplementation on time to improve physical health.

Magnafolate® is a patent protected Crystalline Calcium L-5-methyltetrahydrofolate (L-5-MTHF-Ca) developed by JinKang Hexin in China in 2012.

Magnafolate® is safer, purer, more stable and suitable for a wide range of people including those with MTHFR gene mutations.