Folate, also known as vitamin B9, is one of the essential and vital nutrients. It plays an important function in the body's nervous system.

So, what does folate deficiency affect in the nervous system?

Neural tube defects

Folate is a key nutrient for fetal neural tube development.

Folate deficiency in pregnant women may lead to incomplete closure of the fetal neural tube, triggering neural tube defects such as spina bifida and incomplete closure of the cerebrospinal canal.

Neurodevelopmental disorders

Folate plays an important role in the differentiation, migration and connectivity of nerve cells.

Folate deficiency may interfere with normal neurodevelopment, leading to structural and functional abnormalities in the nervous system, which in turn affects normal brain development.

Neuroinflammation and oxidative stress

Folate deficiency may lead to an increased neuroinflammatory response and oxidative stress.

Neuroinflammation and oxidative stress can damage nerve cells, leading to the development of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

Abnormal neurotransmitter synthesis

Folate is an important coenzyme required for the synthesis of neurotransmitters.

Folate deficiency may lead to abnormal neurotransmitter synthesis, affecting nerve signaling and nerve function.

Magnafolate® is a patent protected Crystalline C Calcium L-5-methyltetrahydrofolate (L-5-MTHF-Ca) developed by JinKang Hexin in China in 2012.

Magnafolate® is safer, purer, more stable and suitable for a wide range of people including those with MTHFR gene mutations.