The importance of controlling JK12A impurities in L-methylfolate

Impurity control in L-methylfolate ingredient is essential as impurities can diminish the biological activity, increase the toxicity, and affect the clinical efficacy of L-methylfolate. JK12A is an oxidative impurity of L-methylfolate. The latest findings demonstrated that JK12A adversely influenced the growth of zebrafish embryos and altered both the heart rate and survival rate in a dose-dependent manner.

Magnafolate is currently the most stringent impurity control raw material in L-methylfolate, known as the purest L-methylfolate on the planet.

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