Magnafolate®  is a patent trademark of C-crystal form of calcium salt L-5-Methyltetrahydrofolate (CAS No. 151533-22-1) by Jinkang Pharma, produced under US Patent No. 9,150,982 along with a better particle size distribution, excellent stability, better dissolution, high potency, bioavailability and safety. Now, Magnafolate ® has been well approved in US GRAS, NDI and FDA.

5-MTHF is an active, naturally occurring form of folate. It’s an essential B vitamin that supports metabolism. Many people don’t get sufficient 5-MTHF because they have intestinal or liver dysfunction or because of their genetic deficiency which makes it difficult to convert folic acid into active 5-MTHF. A deficiency of folic acid has been linked to low-birth-weight infants and neural tube defects, which is reason that Centers for Disease Control recommends folate supplement for all women of childbearing age.

Calcium L-5-MTHF-Ca is a synthetic derivative of folic acid, the predominant, naturally occurring form of folate. It is synthesized by reduction of folic acid to tetrahydrofolic acid followed by methylation and diastereoselective crystallization (in water) of L-5-MTHF as its calcium salt. The product contains variable amounts of water of crystallization. While folic acid needs to be metabolized through several steps to folate cycle.. 

Magnafolate® ,the Manufacturers & Supplier of active folate.