There is widespread agreement that maintaining adequate folate status is critical to prevent diseases due to folate inadequacy (e.g., anemia, birth defects, and cancer). However, there are concerns of potential adverse effects of excess folic acid intake and/or elevated folate status, with the original concern focused on exacerbation of clinical effects of vitamin B-12 deficiency and its role in neurocognitive health. More recently, animal and observational studies have suggested potential adverse effects on cancer risk, birth outcomes, and other diseases.

More details pls refer https://pubmed.ncbi.nlm.nih.gov/33022704/

Unlike folic acid, Magnafolate is a kind of active folate, called L-5-Methyltetrahydrofolate which is the safest folate source on the planet!

A quick view:

USP grade

Patent protected C- Crystal

Safer with MTD≥15g/kg

Highest content L-5-Methyltetrahydrofolate (>85%)

3 years stability at room temperature

Well approved in FDA NDI 920, GRAS in 2016, Certificated by Halal, Kosher..

Magnafolate® ,the Manufacturers & Supplier of active folate.