L-5-Methylfolate:May Reduce Stroke & Heart Attack Risk

L-5-Methylfolate could improve heart and circulatory health by reducing homocysteine and through other mechanisms. 

However, it’s complicated. It might only reduce your risk of heart attack or stroke if you’re folate deficient.


L-5-Methylfolate and active folate may reduce stroke and heart attack risk
Here’s a summary of key evidence that almost reads as a mystery story…

A 2015 study found that men who supplemented with active folate and took enalapril, a drug that lowers blood pressure, lowered their risk of stroke over a 4.5-year period. The results were significant for the folic acid-enalapril group compared to the enalapril-only group. Old studies from the 70’s also appear to show decreased stroke and heart attack risk from increased folate use. 
Reduce Stroke & Heart Attack Risk
On the other hand, some U.S.-based placebo studies didn’t show a decrease in stroke or heart attack risk. This could mean that folate only has this effect when people are deficient. Recall that the USA began fortifying grains in 1998, which could explain some results from the 70’s. People had lower folate levels. 

China does not fortify grains, which means their population may be deficient as well. Some of the old U.S. studies tracked people who had a history of stroke and heart attack. These people may have decreased their risk with medicines and foods other than folate as a response to these events. 

Magnafolate® ,the Manufacturers & Supplier of L-5-Methylfolate. 
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