What Does L-5-methylfolate Do

L-5-methylfolate (together with vitamin B12) functions as a methyl group donor in a range of metabolic and nervous system processes, making it vital to numerous metabolic pathways in the body. L-5-methylfolate plays an essential role in methylation, it enables the conversion of homocysteine to methionine, the production of serotonin and melatonin, and it is indirectly involved in the synthesis of DNA.

There is a well researched link between low folate status and an increased risk of neural tube defects, miscarriages and premature births in pregnant women. This is why folate supplementation, in conjunction with increased consumption of folate rich foods, is now recommended before and during pregnancy.

What Does 5-MTHF Do

L-5-methylfolate is the strongest type of dietary folate. It is the only form naturally found in our circulation, and is therefore the type of folate normally transported into peripheral tissues to be used for cellular metabolism. Many people are not aware that folic acid is a synthetic form of the vitamin, which means it is only found in fortified foods, supplements and pharmaceuticals. It is the most oxidised form of folate and does not possess the coenzyme activity needed by the body. Because of this it must be reduced and methylated to become metabolically active in the body. Within the cell folic acid is reduced to the metabolically active “tetrahydrofolate” form.

Magnafolate® ,the Manufacturers & Supplier of L-5-Methylfolate.
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