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MTHFR stands for Methylenetetrahydrofolate Reductase. It is a key regulatory enzyme in the metabolism of folate. It also refers to a specific gene that plays a major role in the body’s methylation process. Both the enzyme and the gene have the same name, MTHFR.
Recently, people found Children with higher cord UMFA were associated with a greater risk of ASD, while 5mthf will not cause ASD.
Do you know folate, folic acid and 5-methyltetrahydrofolate are not the same thing? Folate, an essential micronutrient, is a critical cofactor in one-carbon metabolism. Mammals cannot synthesize folate and depend on supplementation to maintain normal levels. Low folate status may be caused by low dietary intake, poor absorption of ingested folate and alteration of folate metabolism due to genetic defects or drug interactions.
Strong points for Magnafolate as followed. 1.Magnafolate is the most stable L-5-MTHF Ca 36 months stable at II zone with the longest shelf life. 24 months stable at IVB zone(the study is still on going). It’s also the only form of L-methylfolate which can be stable at the strict condition of IVB zone longer than 6 months.
Unlike folic acid, Magnafolate® will not mask vitamin B12-deficiency and easier to be absorbed by the human organism directly. Also it has been well approved in US. GRAS, NDI and FDA.
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